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BDBM50331327 (E)-4-(2-(thiophen-3-yl)vinyl)benzenesulfonamide::CHEMBL1288802

SMILES: NS(=O)(=O)c1ccc(\C=C\c2ccsc2)cc1

InChI Key: InChIKey=JQHQATMSMAURMY-OWOJBTEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331327   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclooxygenase-2 (COX-2)


(Mus musculus (Mouse))
BDBM50331327
PNG
((E)-4-(2-(thiophen-3-yl)vinyl)benzenesulfonamide |...)
Show SMILES NS(=O)(=O)c1ccc(\C=C\c2ccsc2)cc1
Show InChI InChI=1S/C12H11NO2S2/c13-17(14,15)12-5-3-10(4-6-12)1-2-11-7-8-16-9-11/h1-9H,(H2,13,14,15)/b2-1+
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 440n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of COX-2 mediated PGE2 production in LPS-induced mouse RAW264.7 cells


Bioorg Med Chem Lett 20: 6938-41 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.136
BindingDB Entry DOI: 10.7270/Q2542NVC
More data for this
Ligand-Target Pair