BDBM50331352 CHEMBL1290611::rac-2-(4-(2-chloro-4-nitrophenylsulfonyl)phenyl)-1,1,1-trifluoropropan-2-ol

SMILES CC(O)(c1ccc(cc1)S(=O)(=O)c1ccc(cc1Cl)[N+]([O-])=O)C(F)(F)F

InChI Key InChIKey=OYMRQWMCPFIIRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331352   

LigandPNGBDBM50331352(rac-2-(4-(2-chloro-4-nitrophenylsulfonyl)phenyl)-1...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50331352(rac-2-(4-(2-chloro-4-nitrophenylsulfonyl)phenyl)-1...)
Affinity DataIC50: 105nMAssay Description:Inhibition of human 11beta-HSD1 transfected in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed