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BDBM50331389 CHEMBL1289409::N-((3S,4S)-4-(4-(5-fluoropyridin-2-yl)phenyl)tetrahydrofuran-3-yl)propane-2-sulfonamide

SMILES: CC(C)S(=O)(=O)N[C@@H]1COC[C@@H]1c1ccc(cc1)-c1ccc(F)cn1

InChI Key: InChIKey=NNHDXXVNXHKIOJ-SJLPKXTDSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331389   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel


(Homo sapiens (human))
BDBM50331389
PNG
(CHEMBL1289409 | N-((3S,4S)-4-(4-(5-fluoropyridin-2...)
Show SMILES CC(C)S(=O)(=O)N[C@@H]1COC[C@@H]1c1ccc(cc1)-c1ccc(F)cn1
Show InChI InChI=1S/C18H21FN2O3S/c1-12(2)25(22,23)21-18-11-24-10-16(18)13-3-5-14(6-4-13)17-8-7-15(19)9-20-17/h3-9,12,16,18,21H,10-11H2,1-2H3/t16-,18-/m1/s1
PDB
MMDB

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Article
PubMed
n/an/a>6.30E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]-dofetilide from human hERG


Bioorg Med Chem Lett 20: 7116-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.062
BindingDB Entry DOI: 10.7270/Q2WQ042G
More data for this
Ligand-Target Pair
GRIA2


(HUMAN)
BDBM50331389
PNG
(CHEMBL1289409 | N-((3S,4S)-4-(4-(5-fluoropyridin-2...)
Show SMILES CC(C)S(=O)(=O)N[C@@H]1COC[C@@H]1c1ccc(cc1)-c1ccc(F)cn1
Show InChI InChI=1S/C18H21FN2O3S/c1-12(2)25(22,23)21-18-11-24-10-16(18)13-3-5-14(6-4-13)17-8-7-15(19)9-20-17/h3-9,12,16,18,21H,10-11H2,1-2H3/t16-,18-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 300n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Positive modulation of human GluA2 flip receptor by FLIPR assay


Bioorg Med Chem Lett 20: 7116-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.062
BindingDB Entry DOI: 10.7270/Q2WQ042G
More data for this
Ligand-Target Pair