BDBM30130 CHEMBL1201082::CHEMBL41::Fluoxetin::Fluoxetine::Prozac::US9120771, Fluoxetine::cid_62857

SMILES: CNCC[C@H](c1ccccc1)Oc2ccc(cc2)C(F)(F)F

InChI Key: InChIKey=RTHCYVBBDHJXIQ-UHFFFAOYSA-N

Data: 169 KI  89 IC50  4 Kd  4 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 263 hits for monomerid = 30130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin-conjugating enzyme E2 N (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.58	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.54E+3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.44E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 1B1 (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.75E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Mouse)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A/1B/1D/1F (Rat)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rat)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.810	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Human)	BDBM30130 (Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair