BDBM50331737 2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(trifluoromethyl)phenyl)ethyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl)acetic acid::CHEMBL1290413

SMILES C[C@@H](c1ccc(cc1)C(F)(F)F)n1c2[C@@H](CC(O)=O)CCCc2c2cc(F)cc(c12)S(C)(=O)=O

InChI Key InChIKey=KSSMIJUMUAANAX-DZGCQCFKSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50331737   

TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  0.430nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  338nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  830nMAssay Description:Binding affinity to prostanoid receptor EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  2.27E+3nMAssay Description:Binding affinity to prostanoid receptor EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  4.32E+3nMAssay Description:Binding affinity to prostanoid receptor FP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  4.59E+3nMAssay Description:Binding affinity to prostanoid receptor EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  6.61E+3nMAssay Description:Binding affinity to prostanoid receptor EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  1.55E+4nMAssay Description:Binding affinity to prostanoid receptor IP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataIC50:  1.94E+4nMAssay Description:Antagonist activity at TP receptor in human platelet assessed as thromboxane A2- induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at prostanoid DP1 receptor in human platelet assessed as inhibition of PGD2 induced accumulation of cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed