BDBM50331819 6-[(1,1-Dioxo-tetrahydro-1lambda*6*-thiophen-3-ylmethyl)-amino]-9-fluoro-2H-benzo[c][1,6]naphthyridin-1-one::CHEMBL1290423

SMILES Fc1ccc2c(NCC3CCS(=O)(=O)C3)nc3cc[nH]c(=O)c3c2c1

InChI Key InChIKey=YJQUADKQWWERLA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331819   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50331819(6-[(1,1-Dioxo-tetrahydro-1lambda*6*-thiophen-3-ylm...)
Affinity DataIC50:  512nMAssay Description:Inhibition of JAK2 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed