BDBM50331821 6-(2,6-dichlorobenzylamino)-9-fluorobenzo[c][1,6]naphthyridin-1(2H)-one::CHEMBL1290533

SMILES Fc1ccc2c(NCc3c(Cl)cccc3Cl)nc3cc[nH]c(=O)c3c2c1

InChI Key InChIKey=SVRPJZDUCBNJNX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331821   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50331821(6-(2,6-dichlorobenzylamino)-9-fluorobenzo[c][1,6]n...)
Affinity DataIC50:  53nMAssay Description:Inhibition of JAK2 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed