BDBM50332333 4-amino-2-(4-chloro-3-fluorobenzyl)-4-methyl-1-(4-((S)-5-methyl-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl)piperazin-1-yl)pentan-1-one::CHEMBL1632388

SMILES C[C@@H]1SCc2ncnc(N3CCN(CC3)C(=O)C(Cc3ccc(Cl)c(F)c3)CC(C)(C)N)c12

InChI Key InChIKey=VJUHWZYINXKQFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332333   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50332333(4-amino-2-(4-chloro-3-fluorobenzyl)-4-methyl-1-(4-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50332333(4-amino-2-(4-chloro-3-fluorobenzyl)-4-methyl-1-(4-...)
Affinity DataIC50: 587nMAssay Description:Inhibition of Akt in human LNCaP cell assessed as inhibition of PRAS40 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed