BDBM50332798 CHEMBL1629795::N-(3-Chloro-10H-phenothiazin-10-yl)-3-(dimethylamino)propanamide

SMILES CN(C)CCC(=O)NN1c2ccccc2Sc2cc(Cl)ccc12

InChI Key InChIKey=OGSIAWJVXJZZOI-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50332798   

TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50332798(CHEMBL1629795 | N-(3-Chloro-10H-phenothiazin-10-yl...)
Affinity DataKi: >500nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50332798(CHEMBL1629795 | N-(3-Chloro-10H-phenothiazin-10-yl...)
Affinity DataIC50:  2.60E+4nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50332798(CHEMBL1629795 | N-(3-Chloro-10H-phenothiazin-10-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50332798(CHEMBL1629795 | N-(3-Chloro-10H-phenothiazin-10-yl...)
Affinity DataIC50:  700nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed