BDBM50332807 (8R,9S,10R,13S,14S)-10,13-dimethyl-2,3,7,8,9,10,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[alpha]phenanthren-17(6H)-one::CHEMBL1629804
SMILES C[C@]12CC[C@H]3[C@@H](CCC4=CCCC[C@]34C)[C@@H]1CCC2=O
InChI Key InChIKey=MNOAOFLIFDRILH-QAGGRKNESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50332807
Affinity DataKi: 6.80nMAssay Description:Competitive inhibition of human aromatase extracted from placental microsomes after 5 mins by Dixon plot analysis in presence of [1beta-3H]ADMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:The binding affinity was determined on Cytochrome P450 19A1 by analysis of Dixon plotMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Binding affinity for human placental microsome cytochrome P450 19A1 with 1 uM [1-beta-3H]-androstenedioneMore data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Inhibition of aromatase in human placental microsomes using [1beta-3H]androstenedione as substrate after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human placental aromataseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:In vitro competetitive inhibitory activity was measured on Cytochrome P450 19A1 of human placental microsomesMore data for this Ligand-Target Pair