BDBM50333109 CHEMBL4161639

SMILES NCc1cccc(c1)-c1cccc(c1)C(=O)N[C@H]1CCCc2ccccc12

InChI Key InChIKey=ONRUCWPTBOHFGA-QHCPKHFHSA-N

Data  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333109   

TargetComplement factor D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50333109(CHEMBL4161639)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of recombinant complement factor D catalytic domain (unknown origin) using Z-Lys-thiobenzyl as substrate pretreated for 1 hr followed by s...More data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50333109(CHEMBL4161639)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of 2-((1E,3E,5E)-5-(1-(6-((((3S,5S)-1-((1-carbamoyl-1H-indol-3-yl)carbamoyl)-5-((3-chloro-2-fluorobenzyl)carbamoyl)-3-fluoropyrrolidin-3-y...More data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50333109(CHEMBL4161639)
Affinity DataKd:  2.00E+4nMAssay Description:Displacement of 19F[(S)-methyl 2-((2-(3-(trifluoromethoxy)phenylcarbamoyl)pyrrolidine-1-carboxamido)methyl)benzoate] from complement factor D (unknow...More data for this Ligand-Target Pair