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BDBM50333510 2-(1,4'-bipiperidin-1'-yl)-5-m-tolyl-1,3,4-thiadiazole::CHEMBL1641827

SMILES: Cc1cccc(c1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=IWWVNZMWWFNPCJ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333510   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50333510
PNG
(2-(1,4'-bipiperidin-1'-yl)-5-m-tolyl-1,3,4-thiadia...)
Show SMILES Cc1cccc(c1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C19H26N4S/c1-15-6-5-7-16(14-15)18-20-21-19(24-18)23-12-8-17(9-13-23)22-10-3-2-4-11-22/h5-7,14,17H,2-4,8-13H2,1H3
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Similars

Article
PubMed
60n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK cells after 30 mins by scintillation count...


Bioorg Med Chem Lett 21: 861-4 (2011)


Article DOI: 10.1016/j.bmcl.2010.11.065
BindingDB Entry DOI: 10.7270/Q20V8D24
More data for this
Ligand-Target Pair