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BDBM50333552 2,6-dimethyl-5-(4-methylpiperazin-1-yl)-1-(naphthalen-2-ylsulfonyl)-2,3-dihydroquinolin-4(1H)-one::CHEMBL1642127

SMILES: CC1CC(=O)c2c(ccc(C)c2N2CCN(C)CC2)N1S(=O)(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=YCFBZCBUEYCCEX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333552   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50333552
PNG
(2,6-dimethyl-5-(4-methylpiperazin-1-yl)-1-(naphtha...)
Show SMILES CC1CC(=O)c2c(ccc(C)c2N2CCN(C)CC2)N1S(=O)(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C26H29N3O3S/c1-18-8-11-23-25(26(18)28-14-12-27(3)13-15-28)24(30)16-19(2)29(23)33(31,32)22-10-9-20-6-4-5-7-21(20)17-22/h4-11,17,19H,12-16H2,1-3H3
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Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 21: 698-703 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.007
BindingDB Entry DOI: 10.7270/Q2W37WM6
More data for this
Ligand-Target Pair