BDBM50333850 (R)-2-(7-(4-fluoro-N-(4-fluorobenzyl)phenylsulfonamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid::CHEMBL1643789
SMILES OC(=O)Cc1c2CC[C@H](Cn2c2ccccc12)N(Cc1ccc(F)cc1)S(=O)(=O)c1ccc(F)cc1
InChI Key InChIKey=OHOXPFJGCQEEJL-OAQYLSRUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50333850
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assayMore data for this Ligand-Target Pair
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataKi: 1.57E+3nMAssay Description:Binding affinity to thromboxane receptorMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataKi: 2.29E+3nMAssay Description:Binding affinity to prostanoid DP1 receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at human recombinant CRTH2 receptor expressed in HEK293 cells assessed as inhibition of DK-PGD2-induced intracellular cAMP format...More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Induction of pregnane X receptorMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape changeMore data for this Ligand-Target Pair