BDBM50333955 CHEMBL1644472::exo-(1R,5S)-8-methyl-3-phenoxy-8-azabicyclo[3.2.1]octane

SMILES CN1[C@H]2CC[C@@H]1C[C@H](C2)Oc1ccccc1

InChI Key InChIKey=SYNKGZURWSKSDC-DABQJJPHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333955   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333955(CHEMBL1644472 | exo-(1R,5S)-8-methyl-3-phenoxy-8-a...)
Affinity DataIC50:  86nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333955(CHEMBL1644472 | exo-(1R,5S)-8-methyl-3-phenoxy-8-a...)
Affinity DataIC50:  437nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50333955(CHEMBL1644472 | exo-(1R,5S)-8-methyl-3-phenoxy-8-a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed