BDBM50334080 2-[5-Chloro-2-(1-methyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)-pyrimidin-4-ylamino]-benzamide::CHEMBL1644798

SMILES CN1c2ccc(Nc3ncc(Cl)c(Nc4ccccc4C(N)=O)n3)cc2CCCC1=O

InChI Key InChIKey=OLZPYOIWNSDNMX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334080   

TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334080(2-[5-Chloro-2-(1-methyl-2-oxo-2,3,4,5-tetrahydro-1...)
Affinity DataIC50:  4nMAssay Description:Inhibition of IR kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334080(2-[5-Chloro-2-(1-methyl-2-oxo-2,3,4,5-tetrahydro-1...)
Affinity DataIC50:  85nMAssay Description:Inhibition of human c-Met in human GTL16 cells by cell-based assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334080(2-[5-Chloro-2-(1-methyl-2-oxo-2,3,4,5-tetrahydro-1...)
Affinity DataIC50:  7nMAssay Description:Inhibition of c-MetChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed