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BDBM50334197 7-Chloro-3-[(imidazolidin-2-yl)imino]indazole hydrochloride::CHEMBL1641689

SMILES: Clc1cccc2c(N=C3NCCN3)[nH]nc12

InChI Key: InChIKey=IVRZKTAWAHLCMO-UHFFFAOYSA-N

Data: 1 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334197   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Imidazoline I1


(RAT)
BDBM50334197
PNG
(7-Chloro-3-[(imidazolidin-2-yl)imino]indazole hydr...)
Show SMILES Clc1cccc2c(N=C3NCCN3)[nH]nc12
Show InChI InChI=1S/C10H10ClN5/c11-7-3-1-2-6-8(7)15-16-9(6)14-10-12-4-5-13-10/h1-3H,4-5H2,(H3,12,13,14,15,16)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
30.8n/an/an/an/an/an/an/an/a



Medical University of Gdansk

Curated by ChEMBL


Assay Description
Displacement of [3H]2BFI from imidazoline I1 receptor in Sprague-Dawley rat brain membrane after 45 mins by liquid scintillation counting


Bioorg Med Chem 19: 321-9 (2011)

More data for this
Ligand-Target Pair
Imidazoline I1


(RAT)
BDBM50334197
PNG
(7-Chloro-3-[(imidazolidin-2-yl)imino]indazole hydr...)
Show SMILES Clc1cccc2c(N=C3NCCN3)[nH]nc12
Show InChI InChI=1S/C10H10ClN5/c11-7-3-1-2-6-8(7)15-16-9(6)14-10-12-4-5-13-10/h1-3H,4-5H2,(H3,12,13,14,15,16)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.01E+3n/an/an/an/an/an/a



Medical University of Gdansk

Curated by ChEMBL


Assay Description
Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney membrane after 45 mins by liquid scintillation counting


Bioorg Med Chem 19: 321-9 (2011)

More data for this
Ligand-Target Pair
Alpha-2A adrenergic receptor


(Homo sapiens (Human))
BDBM50334197
PNG
(7-Chloro-3-[(imidazolidin-2-yl)imino]indazole hydr...)
Show SMILES Clc1cccc2c(N=C3NCCN3)[nH]nc12
Show InChI InChI=1S/C10H10ClN5/c11-7-3-1-2-6-8(7)15-16-9(6)14-10-12-4-5-13-10/h1-3H,4-5H2,(H3,12,13,14,15,16)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 73n/an/an/an/a



Medical University of Gdansk

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant alpha2A adrenergic receptor expressed in CHO cells assessed as induction of [35S]GTPgammaS binding after 60 min...


Bioorg Med Chem 19: 321-9 (2011)

More data for this
Ligand-Target Pair