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BDBM50334253 3-(4-ethylpiperazin-1-yl)-1-(4-isopropylphenylsulfonyl)-1H-indole::CHEMBL1642417

SMILES: CCN1CCN(CC1)c1cn(c2ccccc12)S(=O)(=O)c1ccc(cc1)C(C)C

InChI Key: InChIKey=QDYGSCKGDACLLR-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334253   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50334253
PNG
(3-(4-ethylpiperazin-1-yl)-1-(4-isopropylphenylsulf...)
Show SMILES CCN1CCN(CC1)c1cn(c2ccccc12)S(=O)(=O)c1ccc(cc1)C(C)C
Show InChI InChI=1S/C23H29N3O2S/c1-4-24-13-15-25(16-14-24)23-17-26(22-8-6-5-7-21(22)23)29(27,28)20-11-9-19(10-12-20)18(2)3/h5-12,17-18H,4,13-16H2,1-3H3
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Similars

Article
PubMed
8.60n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assay


Bioorg Med Chem Lett 21: 346-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.11.001
BindingDB Entry DOI: 10.7270/Q2P84C5W
More data for this
Ligand-Target Pair