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BDBM50334465 1,10-bis(3-methyl-5,6-dihydropyridin-1(2H)-yl)decane::CHEMBL1643940

SMILES: CC1=CCCN(CCCCCCCCCCN2CCC=C(C)C2)C1

InChI Key: InChIKey=MVMJSRPDOWPATA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334465   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor protein alpha-6 subunit


(Rattus norvegicus)
BDBM50334465
PNG
(1,10-bis(3-methyl-5,6-dihydropyridin-1(2H)-yl)deca...)
Show SMILES CC1=CCCN(CCCCCCCCCCN2CCC=C(C)C2)C1
Show InChI InChI=1S/C22H40N2/c1-21-13-11-17-23(19-21)15-9-7-5-3-4-6-8-10-16-24-18-12-14-22(2)20-24/h13-14H,3-12,15-20H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 37.4n/an/an/an/an/an/a



University of Kentucky

Curated by ChEMBL


Assay Description
Antagonist activity at alpha6 nAChR in rat striatum assessed as inhibition of nicotine-induced [3H]dopamine release


Bioorg Med Chem Lett 21: 88-91 (2010)


Article DOI: 10.1016/j.bmcl.2010.11.070
BindingDB Entry DOI: 10.7270/Q2VT1SDX
More data for this
Ligand-Target Pair