BDBM50334483 CHEMBL1644186::N-((2H-tetrazol-5-yl)methyl)-4-((3-(3,5-dichlorophenyl)-5-(4-(trifluoromethoxy)phenyl)-1H-pyrazol-1-yl)methyl)benzamide
SMILES FC(F)(F)Oc1ccc(cc1)-c1cc(nn1Cc1ccc(cc1)C(=O)NCc1nnn[nH]1)-c1cc(Cl)cc(Cl)c1
InChI Key InChIKey=NCKNXZMACSRNIH-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50334483
Affinity DataIC50: 650nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human GIPR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair