BDBM50334492 4-((3-cyclohexyl-1-(4-(trifluoromethoxy)phenyl)-1H-pyrazol-4-yl)methyl)-N-(2H-tetrazol-5-yl)benzamide::CHEMBL1644174

SMILES FC(F)(F)Oc1ccc(cc1)-n1cc(Cc2ccc(cc2)C(=O)Nc2nnn[nH]2)c(n1)C1CCCCC1

InChI Key InChIKey=GDZNQMSLCBZUND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334492   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334492(4-((3-cyclohexyl-1-(4-(trifluoromethoxy)phenyl)-1H...)
Affinity DataIC50:  5.30E+3nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334492(4-((3-cyclohexyl-1-(4-(trifluoromethoxy)phenyl)-1H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human GIPR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed