BDBM50334653 5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-[1,2,4]triazolo[1,5-c]quinazoline::5-(1H-BENZIMIDAZOL-2-YLMETHYLSULFANYL)-2-METHYL-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLINE::CHEMBL1641615

SMILES Cc1nc2c3ccccc3nc(SCc3nc4ccccc4[nH]3)n2n1

InChI Key InChIKey=VVYNKZKNFFKZDW-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50334653   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PDE5AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PDE1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PDE4D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed