BDBM50334919 (R)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydroquinolin-4-amine::CHEMBL1643513
SMILES CN[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12
InChI Key InChIKey=RYIJMRFACOYPNH-OAHLLOKOSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50334919
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals
Curated by ChEMBL
Sunovion Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 132nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals
Curated by ChEMBL
Sunovion Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 601nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals
Curated by ChEMBL
Sunovion Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sunovion Pharmaceuticals
Curated by ChEMBL
Sunovion Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.25E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair