BDBM50335104 3-(5-Amino-[1,3,4]thiadiazol-2-yl)-1-(thiophen-2-yl)propan-1-one::CHEMBL1650287

SMILES: c1cc(sc1)C(=O)CCc2nnc(s2)N

InChI Key: InChIKey=ODSWRTIXISBLTP-UHFFFAOYSA-N

Data: 1 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50335104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pteridine reductase 1 (Leishmania major)	BDBM50335104 (3-(5-Amino-[1,3,4]thiadiazol-2-yl)-1-(thiophen-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bifunctional dihydrofolate reductase-thymidylate synthase (Leishmania major)	BDBM50335104 (3-(5-Amino-[1,3,4]thiadiazol-2-yl)-1-(thiophen-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50335104 (3-(5-Amino-[1,3,4]thiadiazol-2-yl)-1-(thiophen-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Pteridine reductase 1 (Leishmania major)	BDBM50335104 (3-(5-Amino-[1,3,4]thiadiazol-2-yl)-1-(thiophen-2-y...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair