BDBM50335237 3-(1H-indol-3-yl)-4-[2-(4-oxo-piperidin-1-yl)-5-trifluoromethyl-ylpyrimidin-4-yl]-pyrrole-2,5-dione::3-(1H-indol-3-yl)-4-[2-(4-oxopiperidin-1-yl)-5-(trifluoromethyl)pyrimidin-4-yl]-1H-pyrrole-2,5-dione::CHEMBL1235315

SMILES: c1ccc2c(c1)c(c[nH]2)C3=C(C(=O)NC3=O)c4c(cnc(n4)N5CCC(=O)CC5)C(F)(F)F

InChI Key: InChIKey=MYIILBMNTUDZDH-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 1 PDB ID matches this monomer.

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50335237   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Human)	BDBM50335237 (3-(1H-indol-3-yl)-4-[2-(4-oxo-piperidin-1-yl)-5-tr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	253	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM50335237 (3-(1H-indol-3-yl)-4-[2-(4-oxo-piperidin-1-yl)-5-tr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM50335237 (3-(1H-indol-3-yl)-4-[2-(4-oxo-piperidin-1-yl)-5-tr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50335237 (3-(1H-indol-3-yl)-4-[2-(4-oxo-piperidin-1-yl)-5-tr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair