BDBM50335253 4-Chloro-3'-((2-cyclopentyl-1-oxoisoindolin-5-yloxy)methyl)-biphenyl-3-carboxylic Acid::CHEMBL1651208
SMILES OC(=O)c1cc(ccc1Cl)-c1cccc(COc2ccc3C(=O)N(Cc3c2)C2CCCC2)c1
InChI Key InChIKey=DWTYHCYVKJONSP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50335253
TargetHistamine H1 receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of radioligand binding to human histamine H1 receptorMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK-293 cells assessed as thaillium flux through GIRK channelsMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of radioligand binding to human adrenergic alpha1a receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Positive allosteric modulation activity at rat mGlu2R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of radioligand binding to human adrenergic alpha1d receptorMore data for this Ligand-Target Pair