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BDBM50335291 9-(beta-D-ribofuranosyl)purine::CHEMBL1399702::nebularine::purine ribonucleoside::purine riboside::purine-1-D-ribofuranoside

SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2cncnc12

InChI Key: InChIKey=MRWXACSTFXYYMV-FDDDBJFASA-N

Data: 4 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50335291   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine deaminase


(Homo sapiens (human))
BDBM50335291
PNG
(9-(beta-D-ribofuranosyl)purine | CHEMBL1399702 | n...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2cncnc12
Show InChI InChI=1S/C10H12N4O4/c15-2-6-7(16)8(17)10(18-6)14-4-13-5-1-11-3-12-9(5)14/h1,3-4,6-8,10,15-17H,2H2/t6-,7-,8-,10-/m1/s1
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Article
PubMed
7.00E+3n/an/an/an/an/an/an/an/a



Bar-Ilan University

Curated by ChEMBL


Assay Description
Inhibition of adenosine deaminase


J Med Chem 54: 107-21 (2011)

More data for this
Ligand-Target Pair
Adenosine deaminase


(Bos taurus (bovine))
BDBM50335291
PNG
(9-(beta-D-ribofuranosyl)purine | CHEMBL1399702 | n...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2cncnc12
Show InChI InChI=1S/C10H12N4O4/c15-2-6-7(16)8(17)10(18-6)14-4-13-5-1-11-3-12-9(5)14/h1,3-4,6-8,10,15-17H,2H2/t6-,7-,8-,10-/m1/s1
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MMDB
Article
PubMed
7.00E+3n/an/an/an/an/an/an/an/a



Bar-Ilan University

Curated by ChEMBL


Assay Description
Inhibition of calf intestine adenosine deaminase by Lineweaver-Burk plot analysis


J Med Chem 54: 107-21 (2011)

More data for this
Ligand-Target Pair
Cytidine deaminase


(Mus musculus)
BDBM50335291
PNG
(9-(beta-D-ribofuranosyl)purine | CHEMBL1399702 | n...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2cncnc12
Show InChI InChI=1S/C10H12N4O4/c15-2-6-7(16)8(17)10(18-6)14-4-13-5-1-11-3-12-9(5)14/h1,3-4,6-8,10,15-17H,2H2/t6-,7-,8-,10-/m1/s1
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PubMed
1.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for the inhibitory constant for mouse kidney cytidine deaminase


Citation and Details
More data for this
Ligand-Target Pair
Adenosine deaminase


(Bos taurus (bovine))
BDBM50335291
PNG
(9-(beta-D-ribofuranosyl)purine | CHEMBL1399702 | n...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2cncnc12
Show InChI InChI=1S/C10H12N4O4/c15-2-6-7(16)8(17)10(18-6)14-4-13-5-1-11-3-12-9(5)14/h1,3-4,6-8,10,15-17H,2H2/t6-,7-,8-,10-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
UniChem

Patents


Similars

MMDB
PubMed
1.50E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity against calf intestine adenosine deaminase enzyme


Citation and Details
More data for this
Ligand-Target Pair