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BDBM50335316 4-(1H-Indazol-3-ylamino)-2-phenyl-2H-phthalazin-1-one::CHEMBL1651475

SMILES: O=c1n(nc(Nc2n[nH]c3ccccc23)c2ccccc12)-c1ccccc1

InChI Key: InChIKey=SGLUSJNGNVRYHM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335316   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aurora kinase A/Targeting protein for Xklp2


(Homo sapiens (Human))
BDBM50335316
PNG
(4-(1H-Indazol-3-ylamino)-2-phenyl-2H-phthalazin-1-...)
Show SMILES O=c1n(nc(Nc2n[nH]c3ccccc23)c2ccccc12)-c1ccccc1
Show InChI InChI=1S/C21H15N5O/c27-21-16-11-5-4-10-15(16)20(25-26(21)14-8-2-1-3-9-14)22-19-17-12-6-7-13-18(17)23-24-19/h1-13H,(H2,22,23,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Evotec (UK) Ltd

Curated by ChEMBL


Assay Description
Inhibition of Aurora A by ELISA


J Med Chem 54: 312-9 (2011)


Article DOI: 10.1021/jm101346r
BindingDB Entry DOI: 10.7270/Q29P32MB
More data for this
Ligand-Target Pair