BDBM50335784 2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl]-4-fluorobenzonitrile::CHEMBL1650443::US20240115577, Compound 10

SMILES: CN1C(=O)C=C(N(C1=O)Cc2cc(ccc2C#N)F)N3CCC[C@H](C3)N

InChI Key: InChIKey=IWYJYHUNXVAVAA-UHFFFAOYSA-N

Data: 2 KI  11 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50335784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
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Dipeptidyl peptidase 2 (Rat)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Dipeptidyl peptidase 8 (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Dipeptidyl peptidase 9 (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Prolyl endopeptidase FAP (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 8 (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Human)	BDBM50335784 (2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,...) Show SMILES Show InChI	GoogleScholar	UniChem		5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair