BDBM50336491 3-Hydroxy-benzoic acid::3-Hydroxybenzoate::3-Hydroxybenzoate, II::3-hydroxybenzoic acid::CHEMBL65369
SMILES OC(=O)c1cccc(O)c1
InChI Key InChIKey=IJFXRHURBJZNAO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50336491
Affinity DataKi: 600nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.37E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.17E+3nMAssay Description:Inhibition of human CA6 using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.53E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.53E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.83E+4nMAssay Description:Inhibition of Dicentrarchus labrax CA using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
Affinity DataKd: 6.44E+5nMpH: 8.0Assay Description:The interaction of 3HB6H (25 uM) with substrate analogs was studied in 50 mM Tris-SO4 (pH 8.0). Dissociation constants (Kd) of enzyme-substrate compl...More data for this Ligand-Target Pair
Affinity DataEC50: 2.15E+5nMAssay Description:Agonist activity at human recombinant GPR109a transfected in african green monkey COS-7 cells after 20 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.80E+4nMpH: 8.0Assay Description:The interaction of 3HB6H (25 uM) with substrate analogs was studied in 50 mM Tris-SO4 (pH 8.0). Dissociation constants (Kd) of enzyme-substrate compl...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant PTP1B expressed in CHO cells assessed as p-nitorphenol production after 2 mins by microplate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 1.84E+5nMAssay Description:Agonist activity at human recombinant GPR81 transfected in african green monkey COS-7 cells after 20 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.10E+4nMpH: 8.0Assay Description:The interaction of 3HB6H (25 uM) with substrate analogs was studied in 50 mM Tris-SO4 (pH 8.0). Dissociation constants (Kd) of enzyme-substrate compl...More data for this Ligand-Target Pair