BDBM50336507 4-pyridinecarbohydrazide(Isoniazid)::CHEMBL64::Dow-isoniazid::Hyzyd::INH::ISONICOTINIC ACID HYDRAZIDE(ISONIAZIDE)::Isoniazid (INH)::Isonicotinic acid hydrazide (Isoniazid)::Isonicotinic acid hydrazide(Isoniazid)::Isonicotinylhydrazine::Laniazid::Nydrazid::Rimifon::Stanozide::isoniazid::isonicotinamide::isonicotinhydrazide::isonicotinohydrazide::isonicotinyl hydrazide::pyridine-4-carbohydrazide

SMILES: c1cnccc1C(=O)NN

InChI Key: InChIKey=QRXWMOHMRWLFEY-UHFFFAOYSA-N

Data: 9 KI  23 IC50  1 Kd

PDB links: 12 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 33 hits for monomerid = 50336507   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	<0.400	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Myeloperoxidase (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Myeloperoxidase (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Rat)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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N-glycosylase/DNA lyase (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage migration inhibitory factor (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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3-oxoacyl-[acyl-carrier-protein] synthase 3 (Escherichia coli)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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N-glycosylase/DNA lyase (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.5	37
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Putative FAD-containing monooxygenase MymA (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Isocitrate lyase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.56E+5	n/a	n/a	n/a	n/a	n/a	37
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Bile salt export pump (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Polyphenol oxidase 2 (White button mushroom)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		5.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2A6 (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C8 (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C8 (Human)	BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...) Show SMILES Show InChI	GoogleScholar	UniChem		3.74E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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