BDBM50336579 3-(4-methoxyphenoxy)-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile::CHEMBL1672070

SMILES COc1ccc(Oc2ccc3c4c(C#N)c(=O)nc4c4cccc2c34)cc1

InChI Key InChIKey=MTVXIMCLUYDUHS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50336579   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50336579(3-(4-methoxyphenoxy)-8-oxo-8H-acenaphtho[1,2-b]pyr...)
Affinity DataKi:  122nMAssay Description:Displacement of FAM-Bid peptide from human Mcl-1 after 30 mins by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50336579(3-(4-methoxyphenoxy)-8-oxo-8H-acenaphtho[1,2-b]pyr...)
Affinity DataKi:  258nMAssay Description:Displacement of FAM-Bid from human Mcl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50336579(3-(4-methoxyphenoxy)-8-oxo-8H-acenaphtho[1,2-b]pyr...)
Affinity DataKi:  304nMAssay Description:Displacement of FAM-Bid peptide from human recombinant Bcl2 after 30 mins by by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed