BDBM50336623 CHEMBL1672256::N-(1-(2-chloro-4-fluorobenzoyl)-1H-indol-5-yl)picolinamide

SMILES Fc1ccc(C(=O)n2ccc3cc(NC(=O)c4ccccn4)ccc23)c(Cl)c1

InChI Key InChIKey=AOFDTVQSPBZZNQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336623   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50336623(CHEMBL1672256 | N-(1-(2-chloro-4-fluorobenzoyl)-1H...)
Affinity DataEC50:  1.42E+3nMAssay Description:Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50336623(CHEMBL1672256 | N-(1-(2-chloro-4-fluorobenzoyl)-1H...)
Affinity DataEC50:  1.66E+3nMAssay Description:Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed