BDBM50336799 5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino)]tris[1,3-benzenesulfonate analogue::8,8'-(Carbonylbis(imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino))bisnaphthalene-1,3,5-trisulphonic acid::8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID::8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonyl-imino]]bis-1,3,5-naphthalenetrisulfonic acid(suramin)::8-[(4-methyl-3-{[3-({[3-({2-methyl-5-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)phenyl]carbamoyl}amino)benzene]amido}benzene)amido]naphthalene-1,3,5-trisulfonic acid::CHEMBL265502::Germanin::Suramin hexasodium::US8835659, Suramin::Urea derivative::suramin

SMILES: Cc1ccc(cc1NC(=O)c2cccc(c2)NC(=O)Nc3cccc(c3)C(=O)Nc4cc(ccc4C)C(=O)Nc5ccc(c6c5c(cc(c6)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)C(=O)Nc7ccc(c8c7c(cc(c8)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O

InChI Key: InChIKey=FIAFUQMPZJWCLV-UHFFFAOYSA-N

Data: 10 KI  37 IC50  14 EC50

PDB links: 15 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 65 hits for monomerid = 50336799   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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P2X purinoceptor 6 (Rat)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
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P2Y purinoceptor 2 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a
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DNA primase (Bacillus anthracis)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	8.8	n/a
TBA									Citation and Details
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DNA-dependent protein kinase catalytic subunit (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Protein arginine N-methyltransferase 1 [11-371] (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RmtA (Emericella nidulans)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2Y purinoceptor 2 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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P2Y purinoceptor 6 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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NAD-dependent protein deacetylase HST2 (Baker's yeast)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 2 (Rat)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 1 (Rat)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-dependent 6-phosphofructokinase (Trypanosoma brucei brucei)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.62E+3	n/a	n/a	n/a	n/a	8.0	n/a
TBA									Citation and Details
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Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Pyruvate kinase PKM (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Pyruvate kinase PKM (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Pyruvate kinase PKLR (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Replicase polyprotein 1ab (2019-nCoV)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (Homo sapiens)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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P2X purinoceptor 2 (Rat)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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P2X purinoceptor 3 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
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P2X purinoceptor 4 (Rat)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
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P2Y purinoceptor 4 (Human)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
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P2Y purinoceptor 12 (Rat)	BDBM50336799 (Suramin hexasodium | Germanin | suramin | 8,8'-[Ca...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
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