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BDBM50337020 5-ethyl-2-(phenoxymethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione::CHEMBL1672638

SMILES: CCc1cc(=O)oc2nc(COc3ccccc3)[nH]c(=O)c12

InChI Key: InChIKey=AOSCHBGOTYTUOA-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337020   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hydroxycarboxylic acid receptor 2


(Homo sapiens (Human))
BDBM50337020
PNG
(5-ethyl-2-(phenoxymethyl)-3H-pyrano[2,3-d]pyrimidi...)
Show SMILES CCc1cc(=O)oc2nc(COc3ccccc3)[nH]c(=O)c12
Show InChI InChI=1S/C16H14N2O4/c1-2-10-8-13(19)22-16-14(10)15(20)17-12(18-16)9-21-11-6-4-3-5-7-11/h3-8H,2,9H2,1H3,(H,17,18,20)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.11E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation


ACS Med Chem Lett 2: 171-176 (2011)


Article DOI: 10.1021/ml100251u
BindingDB Entry DOI: 10.7270/Q2DZ08KX
More data for this
Ligand-Target Pair