BindingDB logo
myBDB logout

BDBM50337030 5-(3-cyclobutylpropyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione::CHEMBL1672736

SMILES: FC(F)c1nc2oc(=O)cc(CCCC3CCC3)c2c(=O)[nH]1

InChI Key: InChIKey=PXQQJHLJJRULMK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337030   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hydroxycarboxylic acid receptor 2


(Homo sapiens (Human))
BDBM50337030
PNG
(5-(3-cyclobutylpropyl)-2-(difluoromethyl)-3H-pyran...)
Show SMILES FC(F)c1nc2oc(=O)cc(CCCC3CCC3)c2c(=O)[nH]1
Show InChI InChI=1S/C15H16F2N2O3/c16-12(17)13-18-14(21)11-9(6-2-5-8-3-1-4-8)7-10(20)22-15(11)19-13/h7-8,12H,1-6H2,(H,18,19,21)
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 479n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation


ACS Med Chem Lett 2: 171-176 (2011)


Article DOI: 10.1021/ml100251u
BindingDB Entry DOI: 10.7270/Q2DZ08KX
More data for this
Ligand-Target Pair