BDBM50337126 2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one::CHEMBL1672987::Scaffold, B19::US9266890, IV-2

SMILES: COc1cc(ccc1Nc1ncc2NC(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1

InChI Key: InChIKey=LGLHCXISMKHLIK-UHFFFAOYSA-N

Data: 6 IC50  5 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50337126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activated CDC42 kinase 1 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 7 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Activated CDC42 kinase 1 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase DCLK1 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 7 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 4 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Focal adhesion kinase 1 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Activated CDC42 kinase 1 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 7 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 7 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 7 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>670	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Activated CDC42 kinase 1 (Human)	BDBM50337126 (US9266890, IV-2 | CHEMBL1672987 | Scaffold, B19 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair