BDBM50337304 5-(4-propyl-1H-1,2,3-triazol-1-yl)-1H-indazole::CHEMBL1682335

SMILES CCCc1cn(nn1)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=OPPTYLPEYBJXSL-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50337304   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337304(5-(4-propyl-1H-1,2,3-triazol-1-yl)-1H-indazole | C...)
Affinity DataKi:  108nMAssay Description:Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337304(5-(4-propyl-1H-1,2,3-triazol-1-yl)-1H-indazole | C...)
Affinity DataKi:  756nMAssay Description:Inhibition of JAK2 after 1 hr using biotinylated PDKtide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337304(5-(4-propyl-1H-1,2,3-triazol-1-yl)-1H-indazole | C...)
Affinity DataKi: >1.80E+3nMAssay Description:Inhibition of EGFR after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337304(5-(4-propyl-1H-1,2,3-triazol-1-yl)-1H-indazole | C...)
Affinity DataKi:  2.03E+3nMAssay Description:Inhibition of GSK3-beta after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337304(5-(4-propyl-1H-1,2,3-triazol-1-yl)-1H-indazole | C...)
Affinity DataKi: >3.75E+3nMAssay Description:Inhibition of Pak4 after 1 hr using biotinylated L15 peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337304(5-(4-propyl-1H-1,2,3-triazol-1-yl)-1H-indazole | C...)
Affinity DataKi: >4.90E+3nMAssay Description:Inhibition of Aurora kinase 2 after 1 hr using biotinylated kemptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337304(5-(4-propyl-1H-1,2,3-triazol-1-yl)-1H-indazole | C...)
Affinity DataKi:  8.36E+3nMAssay Description:Inhibition of Pim1 after 1 hr using biotinylated AL1peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337304(5-(4-propyl-1H-1,2,3-triazol-1-yl)-1H-indazole | C...)
Affinity DataKi: >8.88E+3nMAssay Description:Inhibition of KDR after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed