BDBM50337375 CHEMBL1682550::N-cyclohexyl-2-(1H-indazol-5-yl)imidazo[1,2-a]pyridin-3-amine

SMILES C1CCC(CC1)Nc1c(nc2ccccn12)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=GJTDOHMDTQOMGR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50337375   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337375(CHEMBL1682550 | N-cyclohexyl-2-(1H-indazol-5-yl)im...)
Affinity DataKi:  2.31E+3nMAssay Description:Inhibition of Pim1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337375(CHEMBL1682550 | N-cyclohexyl-2-(1H-indazol-5-yl)im...)
Affinity DataKi:  2.48E+3nMAssay Description:Inhibition of Rock2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337375(CHEMBL1682550 | N-cyclohexyl-2-(1H-indazol-5-yl)im...)
Affinity DataKi:  2.61E+3nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337375(CHEMBL1682550 | N-cyclohexyl-2-(1H-indazol-5-yl)im...)
Affinity DataKi:  8.67E+3nMAssay Description:Inhibition of aurora 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed