BDBM50337384 4-(3-(4-(4-fluorophenyl)-5-(1H-indazol-5-yl)-1H-imidazol-1-yl)propyl)morpholine::CHEMBL1682559

SMILES Fc1ccc(cc1)-c1ncn(CCCN2CCOCC2)c1-c1ccc2[nH]ncc2c1

InChI Key InChIKey=HLFSCVDUUVJVCD-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50337384   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337384(4-(3-(4-(4-fluorophenyl)-5-(1H-indazol-5-yl)-1H-im...)
Affinity DataKi:  27nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337384(4-(3-(4-(4-fluorophenyl)-5-(1H-indazol-5-yl)-1H-im...)
Affinity DataKi: >1.45E+3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337384(4-(3-(4-(4-fluorophenyl)-5-(1H-indazol-5-yl)-1H-im...)
Affinity DataKi: >3.75E+3nMAssay Description:Inhibition of Pak4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337384(4-(3-(4-(4-fluorophenyl)-5-(1H-indazol-5-yl)-1H-im...)
Affinity DataKi: >4.90E+3nMAssay Description:Inhibition of aurora 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337384(4-(3-(4-(4-fluorophenyl)-5-(1H-indazol-5-yl)-1H-im...)
Affinity DataKi: >5.45E+3nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337384(4-(3-(4-(4-fluorophenyl)-5-(1H-indazol-5-yl)-1H-im...)
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of Rock2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337384(4-(3-(4-(4-fluorophenyl)-5-(1H-indazol-5-yl)-1H-im...)
Affinity DataKi: >8.75E+3nMAssay Description:Inhibition of Pim1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337384(4-(3-(4-(4-fluorophenyl)-5-(1H-indazol-5-yl)-1H-im...)
Affinity DataKi: >8.88E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed