BDBM50338263 CHEMBL1682017::N-(4-chloro-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(isoquinolin-5-yl)acetamide

SMILES: Clc1csc(NC(=O)Cc2cccc3cnccc23)c1-c1nnc[nH]1

InChI Key: InChIKey=MYLVKAPPYVXQKQ-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338263   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Human)	BDBM50338263 (N-(4-chloro-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Mitogen-activated protein kinase 9 (Human)	BDBM50338263 (N-(4-chloro-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50338263 (N-(4-chloro-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50338263 (N-(4-chloro-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM50338263 (N-(4-chloro-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair