BDBM50338408 CHEMBL1683115::cis-(R)-2-(2,5-difluorophenyl)-1-(4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)cyclohexyl)ethanamine

SMILES N[C@H](Cc1cc(F)ccc1F)[C@H]1CC[C@H](CC1)N1CCn2c(C1)nnc2C(F)(F)F

InChI Key InChIKey=DMNMXJKWEZEVSV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338408   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338408(cis-(R)-2-(2,5-difluorophenyl)-1-(4-(3-(trifluorom...)
Affinity DataIC50: 280nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338408(cis-(R)-2-(2,5-difluorophenyl)-1-(4-(3-(trifluorom...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338408(cis-(R)-2-(2,5-difluorophenyl)-1-(4-(3-(trifluorom...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338408(cis-(R)-2-(2,5-difluorophenyl)-1-(4-(3-(trifluorom...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338408(cis-(R)-2-(2,5-difluorophenyl)-1-(4-(3-(trifluorom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed