BDBM50338431 (R)-ethyl 5-(4-(1-amino-2-(2,5-difluorophenyl)ethyl)piperidin-1-yl)nicotinate::CHEMBL1683137

SMILES CCOC(=O)c1cncc(c1)N1CCC(CC1)[C@H](N)Cc1cc(F)ccc1F

InChI Key InChIKey=WORSZPDWEGVQNR-HXUWFJFHSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338431   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338431((R)-ethyl 5-(4-(1-amino-2-(2,5-difluorophenyl)ethy...)
Affinity DataIC50: >3.50E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338431((R)-ethyl 5-(4-(1-amino-2-(2,5-difluorophenyl)ethy...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338431((R)-ethyl 5-(4-(1-amino-2-(2,5-difluorophenyl)ethy...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338431((R)-ethyl 5-(4-(1-amino-2-(2,5-difluorophenyl)ethy...)
Affinity DataIC50:  82nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338431((R)-ethyl 5-(4-(1-amino-2-(2,5-difluorophenyl)ethy...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed