BDBM50338440 CHEMBL1682974::trans-N-(4-((S)-1-amino-2-oxo-2-(thiazolidin-3-yl)ethyl)cyclohexyl)-4-(trifluoromethoxy)benzamide

SMILES N[C@@H]([C@H]1CC[C@@H](CC1)NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)N1CCSC1

InChI Key InChIKey=BXWYQMPOVCJLIS-NOLJZWGESA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338440   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338440(CHEMBL1682974 | trans-N-(4-((S)-1-amino-2-oxo-2-(t...)
Affinity DataIC50: >3.50E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338440(CHEMBL1682974 | trans-N-(4-((S)-1-amino-2-oxo-2-(t...)
Affinity DataIC50:  170nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338440(CHEMBL1682974 | trans-N-(4-((S)-1-amino-2-oxo-2-(t...)
Affinity DataIC50:  570nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338440(CHEMBL1682974 | trans-N-(4-((S)-1-amino-2-oxo-2-(t...)
Affinity DataIC50:  33nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338440(CHEMBL1682974 | trans-N-(4-((S)-1-amino-2-oxo-2-(t...)
Affinity DataIC50:  690nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed