BDBM50338473 CHEMBL1683107::trans-N-(4-((R)-1-amino-2-(2,5-difluorophenyl)ethyl)cyclohexyl)-N-methyl-1H-indole-3-carboxamide

SMILES CN([C@H]1CC[C@@H](CC1)[C@H](N)Cc1cc(F)ccc1F)C(=O)c1c[nH]c2ccccc12

InChI Key InChIKey=UBQLHRIDEPRNOO-YBOAYWMSSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338473   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338473(CHEMBL1683107 | trans-N-(4-((R)-1-amino-2-(2,5-dif...)
Affinity DataIC50: >3.50E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338473(CHEMBL1683107 | trans-N-(4-((R)-1-amino-2-(2,5-dif...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338473(CHEMBL1683107 | trans-N-(4-((R)-1-amino-2-(2,5-dif...)
Affinity DataIC50:  110nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338473(CHEMBL1683107 | trans-N-(4-((R)-1-amino-2-(2,5-dif...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338473(CHEMBL1683107 | trans-N-(4-((R)-1-amino-2-(2,5-dif...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed