BDBM50338873 CHEMBL1684800::N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-2-methylbenzamide

SMILES: COc1ccc(Cn2ncc(NC(=O)c3cc(NC(=O)Nc4ccc(Cl)c(c4)C(F)(F)F)ccc3C)c2N)cc1

InChI Key: InChIKey=ZJDFSKSBQBPOSK-UHFFFAOYSA-N

Data: 20 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50338873   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	51.6	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Macrophage-stimulating protein receptor (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	277	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	194	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2 (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.13	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 3 (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21.5	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.2	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.42	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.79	n/a	n/a	n/a	n/a	n/a	n/a
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Focal adhesion kinase 1 (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.13	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3 (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.87	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.73	n/a	n/a	n/a	n/a	n/a	n/a
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ALK tyrosine kinase receptor (Human)	BDBM50338873 (N-(5-Amino-1-(4-methoxybenzyl)-1H-pyrazol-4-yl)-5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.71	n/a	n/a	n/a	n/a	n/a	n/a
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