BDBM50339420 3-(4-Chlorophenyl)-3-hydroxy-2-(4-(methylsulfinyl)benzyl)isoindolin-1-one::CHEMBL1688155

SMILES CS(=O)c1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=NQXKIOZJPCCROR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339420   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339420(3-(4-Chlorophenyl)-3-hydroxy-2-(4-(methylsulfinyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed