BDBM50339573 4'-[1-(2-o-Tolyl-ethyl)-1H-[1,2,3]triazol-4-yl]-biphenyl-4-ylamine::CHEMBL1688776

SMILES Cc1ccccc1CCn1cc(nn1)-c1ccc(cc1)-c1ccc(N)cc1

InChI Key InChIKey=MVIUPWZTNZFDLX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50339573   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339573(4'-[1-(2-o-Tolyl-ethyl)-1H-[1,2,3]triazol-4-yl]-bi...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339573(4'-[1-(2-o-Tolyl-ethyl)-1H-[1,2,3]triazol-4-yl]-bi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339573(4'-[1-(2-o-Tolyl-ethyl)-1H-[1,2,3]triazol-4-yl]-bi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed