BDBM50340327 CHEMBL1760957::N-(2-(5,6,7,8-Tetrahydro-2-methoxypyrido[2,3-b]indol-9-yl)ethyl)acetamide

SMILES COc1ccc2c3CCCCc3n(CCNC(C)=O)c2n1

InChI Key InChIKey=PHKIWNIEUVDHIM-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50340327   

TargetMelatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50340327(CHEMBL1760957 | N-(2-(5,6,7,8-Tetrahydro-2-methoxy...)
Affinity DataKi:  0.680nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50340327(CHEMBL1760957 | N-(2-(5,6,7,8-Tetrahydro-2-methoxy...)
Affinity DataKi:  9nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50340327(CHEMBL1760957 | N-(2-(5,6,7,8-Tetrahydro-2-methoxy...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50340327(CHEMBL1760957 | N-(2-(5,6,7,8-Tetrahydro-2-methoxy...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed