BDBM50340500 5,5-dimethyl-1-((2-(methylamino)pyridin-4-yl)methyl)-3-(4-(trifluoromethylthio)phenyl)imidazolidine-2,4-dione::CHEMBL1762176

SMILES CNc1cc(CN2C(=O)N(C(=O)C2(C)C)c2ccc(SC(F)(F)F)cc2)ccn1

InChI Key InChIKey=JCQXXRQZZUXOPX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340500   

TargetInsulin-like growth factor 1 receptor(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50340500(5,5-dimethyl-1-((2-(methylamino)pyridin-4-yl)methy...)
Affinity DataIC50: 43nMAssay Description:Inhibition of autophosphosphorylation of human IGF1R expressed in IGF1-stimulated MCF7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50340500(5,5-dimethyl-1-((2-(methylamino)pyridin-4-yl)methy...)
Affinity DataIC50: 202nMAssay Description:Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in SF21 cells by time resolved-fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50340500(5,5-dimethyl-1-((2-(methylamino)pyridin-4-yl)methy...)
Affinity DataIC50: 202nMAssay Description:Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in SF21 cells after 10 mins by time resolved-fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed